Microcyn HOCl Technology

Microcyn is a stable, highly efficacious pH-neutral wound irrigant based on the science of hypochlorous acid (HOCl).

• HOCl is highly efficient, but under most conditions, an unstable antimicrobial agent that is generated by human cells as a defensive agent.
• Clinically, Microcyn is a biocompatible wound irrigant that is stable, non-toxic, and non-irritating with antimicrobial properties.

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Microcyn HOCL Technology Features

Antimicrobial Efficacy

• HOCl, an ingredient in Microcyn, is 70 times more efficacious than the active ingredient in bleach, sodium hypochlorite (NaOCl).

Non Toxic

• Non-toxic and non-cytotoxic
• Microcyn is very efficacious at levels of free available chlorine (FAC) below the point at which toxicity begins.
• Dilute bleach (Dakin’s solution) requires significantly higher levels of actives and is cytotoxic.

Stable

• Microcyn is stable (24+ month shelf life) life), whereas diluted bleach products such as Dakin’s solution have limited stability requiring generation at the point of use.

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Microcyn HOCl Summary:

Only compound in the world with unique combination

• Broad spectrum and rapidly antimicrobial.
• Effective against viruses, fungi and spores via unique mechanism of action
• No antibiotic resistance seen.
• As safe as saline.
• Accelerates non-infected wound healing via decreased inflammation.

Significant evidence of safety and efficacy

• Biocompatible, non-toxic, non-cytotoxic, non-irritating, non-allergenic.
• 33 clinical trials and numerous published articles.
• Accelerates wound healing 20-30% in multi-study analysis.
• Large human exposure (> 54 million patients to date).

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Example Uses of OroGenix and Microcyn:

In-Office Use

Endocyn 500

• Root canal irrigant.

Microcyn Skin-Wound Solution 500 ml with Sling Label for Hanging

• Cleanser-irrigant.

At-Home Care

OroGenix Oral Hygiene Rinse with Microcyn

• Oral hygiene rinse for at-homecare.

OroGenix Tooth Gel with Microcyn

• Non-fluoride tooth gel for brushing.

Microcyn Wound Gel

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Microcyn Branded Products:

Endocyn, Microcyn OTC Skin-Wound Cleanser, Microcyn Wound Gel

Endocyn with Microcyn

• Root canal irrigant
• 510(k) cleared
• 500 ml (16.9 oz)

Microcyn OTC Skin Wound Cleanser

• Irrigant - cleanser.
• 510(k) cleared.

Two Sizes

• 500 ml (16.9 oz) with sling label.
• 8 oz (237 ml) with squirt cap.

Microcyn Wound Gel

• Topical wound gel
• 510(k) cleared
• 4 oz

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OroGenix At-Home Products with Microcyn

OroGenix Oral Hygiene Rinse and OroGenix Tooth Gel

OroGenix Tooth Gel

• Non-fluoride tooth gel with Microcyn gel.
• 3 fluid ounces (89 ml).

OroGenix Oral Hygiene Rinse

• Oral hygiene rinse with Microcyn

Two Sizes:

• 500 ml (16.9 oz) with graduated measuring cup
• 237 ml (8.5 oz) with graduated measure cup

Documents:
Antimicrobial_Facial_Cleanser_Study
Endocyn_brochure_V3
Endocyn_LSU_Study
Microcyn_Solution_brochure
Microcyn_Test Summary
NPWT_Solution_brochure